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Review Overview

The review module performs quality control and validation of cell-type annotations using configurable flagging rules.

Module Architecture​

Flagging Decision Flow​

Features​

  • Configurable flagging rules: 17 rules across proportion, spatial, biology, and quality categories
  • Multi-column comparison: Compare annotations across cell_type_phenocycler, cell_type_multiomics, etc.
  • Issue tracking: Structured output with severity levels (critical, warning, note)
  • Tissue templates: Expected patterns defined in YAML for tissue-specific validation