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Custom Tissue Example

How to configure CellType-Refinery for a new tissue.

Steps​

  1. Create marker map JSON
  2. Create tissue template YAML
  3. Run initial clustering
  4. Iterate on marker definitions
  5. Validate with domain experts

Tips​

  • Start with major lineages
  • Add subtypes incrementally
  • Use anti-markers to distinguish similar types
  • Validate with known marker expression